Table 3 Validity and completeness of patient categorical features across data sources
Characteristic | Data source | Reference Standard | Concordance | Completeness % (proportion) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
INCR | LHS | QUES | Proportion correct % (n) | Kappa (n, 95 % CI)a | PPV (95 % CI) | NPV (95 % CI) | INCR | LHS | QUES | |||
Demographics | Residence | ---- | ✓ | ✓ | QUES | 100 (67) | ---- | 100 (94.6–100) | ---- | ---- | 100 (119/119) | 100 (67/67) |
Ethnicity | ✓ | ---- | ✓ | QUES | 100 (62) | 1 (62) | 100 (91.2–100) | 100 (85.1–100) | 92.4 (110/119) | ---- | 100 (67/67) | |
Cohabitation status | ---- | ✓ | ✓ | QUES | 60.9 (46) | 0.55 (46, 0.33–0.76) | 71.1 (55.2–83) | 12.5 (2.2–47.1) | ---- | 73.1 (87/119) | 100 (67/67) | |
Mortality | ✓ | ✓ | ---- | INCR | 100 (119) | 1 (119) | 100 (85.1–100) | 100 (96.2–100) | 100 (119/119) | 100 (119/119) | ---- | |
Breast cancer characterization and treatment | Laterality | ✓ | ✓ | ---- | INCR | 97.8 (89) | 0.95 (89, 0.89–1) | 97.3 (86.2–99.5) | 98.1 (89.9–99.7) | 96.6 (115/119) | 75.6 (90/119) | ---- |
Surgery | ✓ | ✓ | ---- | INCR | 100 (97) | ---- | 100 (96.2–100) | ---- | 81.5 (97/119) | 97.5 (116/119) | ---- | |
Breast conserving surgery | ✓ | ✓ | ---- | INCR | 93.8 (97) | 0.86 (97, 0.75–0.97) | 98.4 (91.5–99.7) | 85.3 (69.9–93.6) | 81.5 (97/119) | 94.1 (112/119) | ---- | |
Mastectomy | ✓ | ✓ | ---- | INCR | 92.8 (97) | 0.84 (97, 0.72–0.95) | 91 (81.8–95.8) | 96.7 (83.3–99.4) | 81.5 (97/119) | 94.1 (112/119) | ---- | |
ALN dissection | ✓ | ✓ | ---- | INCR | 79.4 (97) | 0.50 (97, 0.33–0.67) | 75.3 (64.9–83.4) | 100 (80.6–100) | 81.5 (97/119) | 92.4 (110/119) | ---- | |
Radiotherapy | ||||||||||||
Before 2003 | ✓ | ✓ | ---- | LHS claims | 28.6 (7) | ---- | 28.6 (8.2-64.1) | ---- | 26.9 (7/26) | 34.6 (9/26) | ---- | |
2003-2010 | ✓ | ✓ | ---- | LHS claims | 87.5 (8) | ---- | 87.5 (52.9-97.8) | ---- | 8.6 (8/93) | 100 (93/93) | ---- | |
Chemotherapy | ||||||||||||
Before 2003 | ✓ | ✓ | ---- | LHS claims | 44.4 (9) | ---- | 44.4 (18.9-73.3) | ---- | 34.6 (9/26) | 46 (12/26) | ---- | |
2003-2010 | ---- | LHS claims | 91.7 (12) | ---- | 91.7 (64.6-98.5) | ---- | 12.9 (12/93) | 100 (93/93) | ---- | |||
Hormone therapy | ||||||||||||
Before 2003 | ✓ | ✓ | ---- | LHS claims | 0 (1) | ---- | 0 (0–79.4) | ---- | 3.8 (1/26) | 65 (17/26) | ---- | |
2003-2010 | ✓ | ✓ | ---- | LHS claims | 100 (5) | ---- | 100 (56.6-100) | ---- | 5.4 (5/93) | 100 (93/93) | ---- | |
Personal medical history | Hypertension | ---- | ✓ | ✓ | Medical record | 79.1 (67) | 0.55 (67, 0.36-0.74) | 51.7 (34.4-68.6) | 100 (90.8-100) | ---- | 100 (119/119) | 100 (67/67) |
Hyperlipidemia | ---- | ✓ | ✓ | Medical record | 73.1 (67) | 0.46 (67, 0.25-0.66) | 59.4 (42.3-74.5) | 85.7 (70.6-93.7) | ---- | 100 (119/119) | 100 (67/67) | |
Renal failure | ---- | ✓ | ✓ | Medical record | 100 (67) | ---- | ---- | 100 (94.6-100) | ---- | 100 (119/119) | 100 (67/67) | |
Rheumatoid arthritis | ---- | ✓ | ✓ | Medical record | 97 (67) | 0.65 (67, 0.21-1) | 50 (15–85) | 100 (94.3-100) | ---- | 100 (119/119) | 100 (67/67) | |
Diabetes | ---- | ✓ | ✓ | Medical record | 97 (67) | 0.93 (67, 0.83-1) | 90.5 (71.1-97.4) | 100 (92.3-100) | ---- | 100 (119/119) | 100 (67/67) | |
Osteoporosis | ---- | ✓ | ✓ | Medical record | 68.7 (67) | 0.37 (67, 0.14-0.59) | 67.9 (49.3-82.1) | 69.2 (53.6-81.4) | ---- | 100 (119/119) | 100 (67/67) | |